Maintaining optimal health includes circadian alignment. Through the perspective of chronobiology and drawing from mystical concepts associated with Shabbat’s 25-hour duration, this platform suggests a shift from the current 24-hour solar days to 25-hour days for improved alignment with the lunar day. This modification could enhance defense against diseases linked to Circadian Rhythm Disruption (CRD) and enable us to generate multiple intraday ‘biological prime time’ episodes.